Browsing by Author "Jawahar, Shabnam"
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OtherItem Open Access Anthelmintic Resistance - An Emerging global risk?(TANUVAS, 2012) Jeyathilakan, N.; Sundar, S.T. Bino; Soundararajan, C.; Gomathinayagam, S.; Raman, M.; Mathialagan, P.; Manikkavasagan, I.; Jawahar, Shabnam; Thenmozhi, V.; Karthik, M.; Basith, S. AbdulArticleItem Open Access Comparative immunoprophylactic efficacy of Haemonchus contortus recombinant enolase (rHcENO) and Con A purified native glycoproteins in sheep(2015) Aravindhan, K.; Jawahar, Shabnam; Manikkavasagan, I.; Azahahianambi, P.; Raman, M.; TANUVASHaemonchus contortus is the most economically important blood feeding nematode parasite of sheep and goats all over the world. Enolase in helminth parasites is a multi-functional enzyme which involves in glycolysis and host tissue invasion. In this study, the recombinant H. contortus enolase (rHcENO) was evaluated for its immunoprophylactic efficacy in sheep along with Con A purified native glycoproteins in a vaccine challenge trial. Group I and Group II experimental sheep were immunized thrice with rHcENO and Con A purified native glycoproteins along with Montanide ISA 61 VG adjuvant. The animals were challenged with 5000 L3 stage active H. contortus larvae after 21 days of third immunization. A significant increase in the IgG titre was observed in rHcENO and Con A purified native glycoproteins immunized animals as compared to the control animals. Immunoprotective efficacy of Con A purified native glycoproteins was comparatively higher than rHcENO antigen.ArticleItem Open Access Comparative immunoprophylactic efficacy of Haemonchus contortus recombinant enolase (rHcENO) and Con A purified native glycoproteins in sheep(Elsevier, 2015-04) Kalyanasundaram, Aravindan; Jawahar, Shabnam; Ilangopathy, Manikkavasagan; Palavesam, Azahahianambi; Raman, Muthusamy; TANUVASHaemonchus contortus is the most economically important blood feeding nematode parasite of sheep and goats all over the world. Enolase in helminth parasites is a multi-functional enzyme which involves in glycolysis and host tissue invasion. In this study, the recombinant H. contortus enolase (rHcENO) was evaluated for its immunoprophylactic efficacy in sheep along with Con A purified native glycoproteins in a vaccine challenge trial. Group I and Group II experimental sheep were immunized thrice with rHcENO and Con A purified native glycoproteins along with Montanide ISA 61 VG adjuvant. The animals were challenged with 5000 L3 stage active H. contortus larvae after 21 days of third immunization. A significant increase in the IgG titre was observed in rHcENO and Con A purified native glycoproteins immunized animals as compared to the control animals. Immunoprotective efficacy of Con A purified native glycoproteins was comparatively higher than rHcENO antigen.OtherItem Open Access Deworming Dogs and Cats(TANUVAS, 2012) Soundararajan, C.; Raman, M.; Mathialagan, P.; Sundar, S.T. Bino; Jeyathilakan, N.; Gomathinayagam, S.; Subadhra, Subhra; Jawahar, Shabnam; Basith, S. AbdulOtherItem Open Access Deworming Sheep and Goats(TANUVAS, 2012) Soundararajan, C.; Raman, M.; Mathialagan, P.; Sundar, S.T. Bino; Jeyathilakan, N.; Gomathinayagam, S.; Manikkavasagan, I.; Deepika, R..B.; Jawahar, Shabnam; Subadhra, Subhra; Basith, S. AbdulOtherItem Open Access Immunization with Hidden Antigen H-Gal-GP Against Haemonchus Contortus in Sheep(TANUVAS, Chennai, 2011-12) Jawahar, Shabnam; Ramanathan, M.; Basith, S. Abdul