Browsing by Author "Doley, Probal Jyoti"
Now showing 1 - 1 of 1
Results Per Page
Sort Options
ThesisItem Open Access Histological And Histochemical Changes In The Liver Of Buffalo During Prenatal Development(Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 2004) Doley, Probal Jyoti; Roy, K. S.The present study was conducted to elucidate the gross morphology, histomorphology and histochemistry of liver during prenatal development in 18 buffalo foetuses. Gross morphological studies revealed that the liver was rounded in shape up to 90 days and a positive correlation was found between the size of the liver and its CRL. Histomorphologically up to 74 days the capsule of the liver was made up of a single layer of maturing collagen and reticular fibre and by 136 days well developed capsule was seen. The thickness of the capsule increased with age and subcapsular blood vessels were seen in liver section of 300 days. Stroma of the liver up to 105 days was mainly made up of mesenchymal and maturing collagen and reticular fibres. Initiation of hepatic lobulation was first seen in foetuses of 136 days with the formation of central vein. Fully formed portal triad was seen from later part of Group III. Typical radial arrangement of the hepatocytes around the central vein was seen from. 176 days onwards. The hepatocytes were irregularly shaped in all the age groups with a centrally located oval nucleus having one or more prominent nucleoli. Hemopoietic activity of the liver was prominent in Group I but it showed a gradual decline from 136 days onwards. The number of Kupffer cells were also high dur ing peak hemopoietic activity per iods but gradually decreased with the decrease in hemopoietic activity. The distribution of acid and neutral polysaccharide and basic protein showed a gradual increase from weak to moderate/strong with increase in age but the distribution of sudanophilic lipids showed a gradual decrease from strong to weak with increase in age.