Browsing by Author "Barvalia, Devshibhai R."
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ThesisItem Open Access CLINICOPATHOLOGIC EVALUATION OF ESCHERICHIA COLI LIPOPOLYSACCHARIDE INDUCED ARTHRITIS IN BUFFALO CALVES(AAU, Anand, 1988) Barvalia, Devshibhai R.; Parsania, R. R.The experiment was undertaken in buffalo calves to study the clinicopathology of E. coli LPS induced arthritis and to evaluate therapeutic utility of intra-articular dexamethesone. The study was carried out on 12 buffalo calves divided into two equal groups (Group I & II). Arthritis of left knee joint was successfully induced in all the animals by intra-articular administration of E.coli LPS at the dose rate of 0.4µg/kg body weight. Group I sarved as control and no treatment was given. In group II, 4 mg of dexamethasone was administered intra-articularly, 5 minutes after E.coli LPS injection. All the animals were observed for 96 hours.