Browsing by Author "Ashu Sharma"
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ThesisItem Open Access A Study On The Pathophysiology Of Urolithiasis And Chemical Composition Of Uroliths In Dogs(Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 2001) Ashu Sharma; V. K. SobtiThe present study was undertaken on seventeen clinical cases of dogs to assess pathophysiological changes and chemical composition of the uroliths. All the 17 dogs were categorised into three groups depending upon the location of calculi. All the 17 dogs were male and were in the age group of 2-14 years. Breedwise, urolithiasis were more prevalent in smaller breeds than in larger breeds. Body temperature, hemoglobin, TLC were near normal on the day of presentation whereas respiration rate, PCV was moderately elevated in dogs of all the three groups before surgery. BUN and creatinine were elevated on the day of presentation but returned to normal 15 days after the surgery. The venous blood pH and plasma HC0-3 were in the lower range before surgery which depicted metabolic acidosis. Radiography proved to be an important diagnostic tool for urolith detection. The calcium oxalate uroliths being radiodense could be easily diagnosed. The microscopic examination of urine revealed predominantly calcium oxalate crystals and calcium phosphate crystals. In addition to it, calcium carbonate, uric acid, ammonium and than oxalate were also noted. The urine pH of !.. /the 17 d'; 3 varied from 6.0-8.0 and thus acidic urine was found to be risk factor for occUrrence of calcium oxalate urolith formation. The uroliths retrieved when evaluated were mainly calcium oxalate and calcium phosphate. The number of uroliths varied from single to multiple. They had varied shapes, sizes with irregular or smooth surfaces. All the dogs were observed for a period of 7-8 months for any recurrence of urolithiasis Since in the present study more emphasis was given on making dietary alterations and endogenous metabolic changes were not checked so reason for the recurrence of urolithiasis in two dogs could not be established