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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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20021
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Subject: Veterinary Pharmacology × Author: Barot, Deepak K. × Start date: 1982 ×
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    ThesisItemOpen Access
    STUDIES ON PHARMACOKINETICS OF ENROFLOXACIN IN WHITE LEGHORN HENS
    (AAU, Anand, 2002) Barot, Deepak K.; Thaker, A. M.
    The present study was conducted to determine the pharmacokinetics of enrofloxacin after single dose intravenous and oral administration in White leghorn hens. Plasma concentrations of enrofloxacin and its metabolite ciprofloxacin were determined by High Performance Liquid Chromatography (HPLC). After intravenous administration, the plasma concentration- time curve was characteristic of a two compartment open rnodel whereas, it was best fitted to one compartment open model following oral administration. Following single dose (10 mg/kg of body weight) intravenous administration of enrofloxacin, the therapeutically effective plasma concentration (>=0.10 µg.ml-1) was maintained for up to 12 hours."The drug was rapidly and extensively distributed [t1/2α: 0.22 ± 0.04 h ; Vd(area); 2.14 ± 0.15 1 kg-1 ] and rapidly eliminated (t1/2β; 4.52 ± 0.52 h) from the body with a clearance rate (CIB) of 5.59 ± 0.27 ml min-1 kg-1. An active metabolite, ciprofloxacin was detected in plasma with peak concentration of 0.30 ± 0.06 µg.ml-1 at 2 hours following intravenous administration of enrofloxacin. Enrofloxacin gets de-ethylated to ciprofloxacin and the metabolic conversion accounts for 7.06 percent of the parent drug. The AUC and MRT values were 2.11 ±0.14 µg.h-1ml-1 and 10.36 ± 0.52 hours, respectively.