Geetha, MPalanivel, KMSelvaraju, G, et al.TANUVAS2020-02-032020-02-032016http://krishikosh.egranth.ac.in/handle/1/5810142396TNV_IVPH_2016_14(1)55-57The present study was carried out retrospectively to assess the risk factors and epidemiological significance of leptospirosis in humans in Namakkal region of Tamil Nadu, India. A total of 345 human sera samples referred by physicians as suspected cases of leptospirosis from Namakkal region of Tamil Nadu were screened by dark field microscopy. Prevalence of leptospirosis in human was 72.5 per cent out of 345 cases. Higher positive rates were noticed in males (70.4%). Relative risk of 1.2 for males indicates that males are at higher risk of developing leptospirosis than females. Prevalence of leptospirosis was high in patients of 21-30 years age group and occupation wise it was found high in students. Higher rates of leptospirosis were noticed during monsoon season in Namakkal region. The control of leptospirosis in humans include vaccination of animals, rodent control, good hygiene and creating public awareness by education which is of utmost importance.enVeterinary ScienceArticle