Venkataraman, KSNedunchelliyan, SJohn, Mathew C.TANUVAS2022-08-032022-08-031993https://krishikosh.egranth.ac.in/handle/1/5810186038TNV_CRN_1993_22(4)140-142Five dogs were experimentally inoculated with virulent Leptospira interrogans serovar Icterohaemorrhagiae and the disease spectrum was studied. Febrile reaction was observed for 4-7 days after infection. The clinical signs observed were pyrexia, anorexia, depression, congested conjunctiva and diarrhoea. Leptospiraemia was observed during the febrile period mostly on PID 4,5, 6 and isolation of leptospires was possible during the fist week. Leptospiraemia was first detected on PID-7 and intermittent after PID-2l. The kidney sections revealed leptospires.EnglishVeterinary ScienceArticle