Chandrashekara Murthy, V.Krishanaswamy, A.Devaraj, M.Girish Kumar, V.Ramachandra, S.G.Mahesha, N.2016-11-032016-11-032011-07-15http://krishikosh.egranth.ac.in/handle/1/83699PG Thesisstudy was conducted to evaluate the metabolic profiles of pregnant Bannur sheep of Karnataka, with the objective to identify the metabolic changes during various stages of pregnancy and also to associate the biochemical profiles in maternal serum to different stages of pregnancy and of growing fetus. Thirty pregnant ewes were categorized in to three equal sized groups (n=10) of early, mid and late gestation using ultra sound findings. Blood glucose, total protein, Albumin, globulin, creatinine, cholesterol, blood urea, serum calcium and phosphorus were estimated at different stages of gestation. The blood glucose decreased significantly from early to late pregnancy. The total protein, globulins and urea and were higher early pregnancy compared to their level at mid and late pregnancy. In contrast albumin concentration increased from early to late pregnancy. The serum cholesterol at peak during early pregnancy and reduced significantly by mid pregnancy with no further significantly falls during late pregnancy. Whereas serum creatinine concentration has shown no significant difference as pregnancy advance. The serum calcium increased significantly to early to mid, mid to late pregnancy whereas no change in phosphorus levels were observed from early to late pregnancy. The magnitude of changes was greater towards the end of gestation could be attributed to the nutrient requirements of ewes. The present study clearly demonstrate the increased nutritional requirement of pregnant ewes, this fact necessitates better managerial practices during last month of gestation to reduce the possibilities of occurrence of metabolic disordersenMetabolic profile, Bannur breed, pregnant ewes, UltrasonographyThesis