Suresh, K (MAJOR)Lakshmi Rani, NSreenu, MakkenaNAGAVENI, CHEKURI2022-10-192022-10-192022-03https://krishikosh.egranth.ac.in/handle/1/5810189160THESESThe present study was undertaken to record the occurrence of pyoderma and also to study the clinical symptomatology, haemato-biochemical findings, antibiotic susceptibility pattern and to assess the therapeutic regimen in dogs affected with pyoderma. The occurrence of dermatological disorders among 1443 cases presented to the small animal medical ward recorded was 24.67 (356) per cent of which suggestive of pyoderma constituted 10.60 (153/1443) per cent of the total cases and 42.98 per cent of the total dermatological disorders. The type wise occurrence of pyoderma in the present study revealed highest occurrence of 79.73 % for superficial pyoderma followed by surface (14.86 %) and least for deep pyoderma (5.41%). Occurrence of pyoderma in relation to age group, breed and gender revealed highest occurrence in 1-3 years old dogs, Labrador Retriever breed and Non descriptive breed and male dogs. The clinical signs observed in dogs affected with surface pyoderma were alopecia, pruritus, erythema, hot spots whereas in superficial pyoderma the signs include alopecia, pruritus, erythema, pustules, papules, epidermal collarettes, scales, crusts, plaques and moth-eaten appearance while in deep pyoderma alopecia, pruritus, nodules, exudation and cellulitis. Diagnosis of pyoderma was done based on the clinical signs, cytology, isolation and identification of bacteria. Isolation and Identification of different bacteria by cultural examination and biochemical tests revealed that highest percent isolated was Staphylococcus spp. alone followed by mixed colonies of Staphylococcus spp.+ Pseudomonas spp., Staphylococcus spp.+ Klebsiella spp., Staphylococcus spp.+ Klebsiella spp.+ Pseudomonas spp., Staphylococcus spp. + Escherichia coli and least isolated was Staphylococcus spp. +Escherichia coli + Pseudomonas spp. Antibiotic susceptibility test conducted on whole culture and pure cultures revealed highest susceptibility with amikacin followed by cefpodoxime, ciprofloxacin, amoxycillin clavulanic acid, cefadroxil, cephalexin and resistance to erythromycin, clindamycin and cotrimoxazole. Underlying factors noticed in dogs affected with pyoderma were tick infestation, lice infestation, flea infestation, demodicosis and Malassezia dermatitis. Haemato biochemical findings revealed significant decrease in mean values of haemoglobin, lymphocytes and albumin. The mean values of TLC, neutrophils and globulin increased significantly whereas non significant increase in eosinophils, monocytes and total protein values were noticed. Therapeutic trial conducted by using three different antibiotics viz., cefpodoxime proxetil, amoxycillin clavulanic acid and enrofloxacin were proved to be efficacious in the treatment of superficial pyoderma in dogs.EnglishThesis