Dr. J.G. SarvaiyaK.Z.Patani2017-10-032017-10-032005http://krishikosh.egranth.ac.in/handle/1/5810032025Cefepime, a fourth-generation semi-synthetic broad spectrum cephalosporin has bactericidal action against broad range of bacteria including those that are resistant to conventional antibacterial drugs. The present study was designed to investigate pharmacokinetics of cefepime in Surti goats following single dose intravenous and intramuscular administration at the dose rate of 10 mg kg-1 of body weight. Drug concentration in serum was determined using High Performance Liquid Chromatography (HPLC). Following intravenous and intramuscular administration, the serum concentration-time curves were characteristic of a two compartment open model.enVeterinary PharmacologystudiesThesis