SURYANARAYANA, C(MAJOR)TIRUMALA RAO, D.S.SADASIVA RAO, KMURALI KRISHNA, MALLELA2018-08-232018-08-232003-09http://krishikosh.egranth.ac.in/handle/1/5810067122THESESABSTRACT : The clinical investigation on renal failure in dogs was aimed at examining the various factors like incidence, history and clinical findings, diagnostic features, conservative medical therapy and its efficacy associated with renal failure. Twenty one dogs were diagnosed to suffer from renal failure on the basis of biochemical alteration such as increased BUN and serum creatinine and urine analysis and they were subjected to conservative therapy. Of the 21 dogs presented, 11 dogs completely recovered and 10 dogs died following therapy. Incidence of renal failure in relation to age, breed and sex revealed it, higher incidence in middle age to old age dogs, German Shepherd and Pomeranian breeds and in male dogs. Anorexia, polydipsia, polyuria were the common clinical history and vomiting was the major clinical symptom. Melena and oral ulcers were also found in some of the dogs. Azotemia, hyperphosphatemia, hypercholesterolaemia were the most important biochemical alterations. Normocytic normochromic anemia was the major haematological finding and there was insignificant change in haematological parameters following therapy in survived dogs. BUN and Serum creatinine levels significantly (P<0.01) decreased in survived dogs following therapy. No significant difference was observed in serum calcium and serum glucose levels before and after treatment in survived dogs. Serum phosphorus levels were significantly (P<0.05) decreased following therapy in survived dogs.ennullThesis