Sidhu, AnjaliSarao, Navjot Singh2017-12-042017-12-042017http://krishikosh.egranth.ac.in/handle/1/5810036886Chalcone is a generic term used to describe compounds with the 1,3-diphenylprop-2-en-1-one framework. On synthetic ground, chalcones are synthesized by Claisen-Schmidt condensation reaction which involved the base mediated reaction of andifferent aldehydeswith different ketone in presence of strong bases like sodium hydroxide and potassium hydroxide. In the present study, series of novel halogenated chalcones (1-14) were synthesized through ClaisenSchmidt condensation reaction between different halogenated aldehydes and α, β-unsaturated halogenated ketonesunder basic conditions. The synthesized compounds were formulated as nano aqua emulsions using oleic acid as oil phase with Tween 20 as surfactant,under ultrasonic irradiation. Antifungal activity of prepared chalcone nanoemulsions was tested against various phytopathogenic fungi viz. Pyriculriagrisea, Dreschslera oryzae, Colletotrichum falcatum and Ustilago hordei. The results indicated that the various synthesized halogenated chalcones showed mild activity against various fungi.ennullThesis