Single, NeenaDhar, Parul2017-06-032017-06-032014http://krishikosh.egranth.ac.in/handle/1/5810015781Feeding of different concentrations of triptolide i.e. 0.15, 0.20 and 0.25% in bait to male and 0.10, 0.15 and 0.20% to female B. bengalensis for 15 days duration in bi-choice feeding tests revealed significantly (P≤0.05) low consumption of treatment bait from that of untreated bait. Autopsy of male rats immediately and after 30 and 60 days of treatment withdrawal revealed significant reduction in weights of reproductive organs; decrease in sperm motility, viability and density and increase in sperm abnormality in rats of treated groups. Histomorphology of testis revealed a significant decrease in diameter of seminiferous tubules and number of different germ cells indicating effect of triptolide on spermatogenesis and spermeiogenesis. Autopsy of female rats after 15 and 30 days of treatment withdrawal revealed significant reduction in weights of ovary and uterus and increase in duration of estrous cycle in rats of treated groups. Histomorphology of uterus and ovary revealed significant antifertility effects of triptolide. The plasma levels of total proteins and enzymes were found increased significantly in all the treated groups of male and female rats. No effect of treatment was observed on weights of vital organs and plasma levels of hormones. Rodent control experiment conducted in sugarcane crop by integrating 0.25% triptolide treatment with 0.005% bromadiolone treatment at the interval of 15 days revealed significant antifertility effects in male rats trapped after 60 days of triptolide treatment. Present study suggests use of triptolide in integration with chemical control for management of post control rodent population rebuildup in crop fields.enrodents, biological phenomena, land resources, organic compounds, diseases, crops, sugarcane, developmental stages, control methods, proteinsThesis