Chandini, Sakthi DCharulatha, MLegadevi, RMeignanalakshmi, STANUVAS2019-01-082019-01-082018-10http://krishikosh.egranth.ac.in/handle/1/5810089242TNV_Ijcmas_2017_6(10)3488-3495In the present study keratin was extracted from chicken feather using the reductants beta mercaptoethanol, urea and SDS. The extracted keratin was lyophilised and was used to prepare hydrogel. Prepared hydrogel was characterized using SEM and FTIR. The prepared keratin hydrogel was used for encapsulation of tetracycline. The percentage of drug encapsulation in keratin hydrogel was found to be 92.5%. The in vitro release of tetracycline from keratin hydrogel was carried out in PBS for 24hrs and was found to be released in a slow and sustained manner.enVeterinary ScienceArticle