DR. VENKANAGOUDA DODDAGOUDARKAVYA J C2024-09-132024-09-132024https://krishikosh.egranth.ac.in/handle/1/5810214473The current study was conducted with three objectives viz. to study the incidence and type of uterine torsion in buffaloes, to compare the prognostic parameters in the uterine torsion cases with normal parturient buffaloes and to study the therapeutic approaches with or without using isoxsuprine for uterine torsion affected buffaloes. First, a retrospective study was conducted to analyze five-year clinical data to find out the incidence and type of uterine torsion in buffaloes. Secondly, blood, serum and peritoneal fluid samples from 17 buffaloes with uterine torsion were analyzed for hematological, biochemical and enzymatic parameters, as well as CRP and MDA and compared with 6 normally calved buffaloes. Thirdly, the torsion-affected buffaloes were divided into two groups, one receiving isoxsuprine prior to detorsion attempts and the other group kept as control. The retrospective incidence study showed that uterine torsion was the leading cause of maternal dystocia in buffaloes, comprising 46.49% of difficult deliveries, occurring mainly at full term. Torsions were predominantly post-cervical and right sided, with angles typically ranging from 90° to 180°. Among the parameters studied, TLC, Creatinine, BUN, SGOT and CK increased significantly (P<0.05) in torsion affected buffaloes compared to normal parturient buffaloes accompanied by reduced TEC, lymphocytopenia and hypomagnesemia. Further, among the torsion affected buffaloes, decreased Hb, leukocytosis, increased Creatinine, BUN, SGOT, SGPT, CK, CRP, MDA and hypomagnesemia were consistent with poor prognosis (P<0.05). Administration of isoxsuprine marginally improved (P>0.05) detorsion success along with dam survival. To conclude, post-cervical, right sided uterine torsion emerged as a primary cause of dystocia in buffaloes typically occurring between 90-180 degrees. Parameters such as Creatinine, BUN, SGOT, SGPT, CK, CRP, MDA and Mg serve as valuable indicators for assessing the prognosis of uterine torsion. Additionally, administering isoxsuprine before detorsion may potentially aid in detorsion and enhance the dam's chances of survival.EnglishThesis