Pratheepa, K.Balachandran, C.TANUVAS2018-04-232018-04-232018-04http://krishikosh.egranth.ac.in/handle/1/5810044342TNV_IVJ_2018_95(4)76-78The present study was designed to examine the expression of cytokeratin (CK 8 and 18) and vimentin in DMBA (7,12-dimethylbenz[a] anthracene) induced rat mammary carcinogenesisby immunohistochemical analysis. Twentyfour female Sprague-Dawley rats were equally distributed to form the control, DMBA, tamoxifen (Standard drug) and Withaferin A groups. Mammary tumours were collected on the 120th day after initial dose of DMBA administration. Increased cytoplasmic expression of cytokeratin and vimentin were observed in all the DMBA administered groups and oral administration of Withaferin A did not reduce the tumour burden.enVeterinary ScienceArticle