Senthilkumar, P.Arivuchelvan, A.Jagadeeswaran, A.Subramanian, N.Senthilkumar, C.Mekala, P.TANUVAS2018-07-202018-07-202014http://krishikosh.egranth.ac.in/handle/1/5810061330The study was conducted to formulate the enrofloxacin solid lipid nanoparticles (SLNs) with sustained release profile and improved pharmacological activity. The enrofloxacin SLNs were prepared using tripalmitin as lipid carrier, tween 80 and span 80 as surfactants and poly vinyl alcohol (PVA) as a stabilizer by a hot homogenization coupled with ultrasonication method. The formulation were characterized for particle size, polydispersity index, zeta potential (using dynamic light scattering), shape (using atomic force microscopy), drug encapsulation efficiency (using by dialysis and ultracentrifugation methods), and in vitro drug release (using by dialysis).en-USVeterinary ScienceVeterinary Pharmacology and ToxicologyBook chapter