Nandhini, SMadheswaran, RBalasubramaniam, GA., et al.,TANUVAS2023-06-142023-06-142022https://krishikosh.egranth.ac.in/handle/1/5810197595TNV_IJVP_2022_46(4)277-282A study was conducted to elucidate the altered clinico-pathological parameters in diagnosis and prognosis of infl ammatory mammary carcinomas in bitches. Blood and serum samples were collected from 30 each normal and tumor bearing bitches for haemato-biochemical analysis. A signifi cant (P<0.05) reduction of total erythrocyte count and highly signifi cant (P<0.01) reduction of packed cell volume were noticed in tumor aff ected bitches. A signifi cant (P<0.05) elevation of mean corpuscular haemoglobin and highly signifi cant (P<0.01) elevation of mean corpuscular haemoglobin concentration and total leucocyte count were observed in mammary tumor aff ected dogs. A signifi cant (P<0.05) increase in total cholesterol and highly signifi cant (P<0.01) increase in alanine transaminase, aspartate transaminase, alkaline phosphatase and potassium values were noticed in tumor bearing bitches. Highly signifi cant (P<0.01) reduction in albumin and signifi cant (P<0.05) reduction in calcium were also noticed. An elevation of superoxide dismutase, reduced glutathione, glutathione peroxidase and lipid peroxidase values whereas reduction of catalase value were noticed in the tumor tissues. Histopathologically, the tumors were classifi ed as benign (2) and malignant (28) tumors with infi ltration of infl ammatory cells in 18 cases. The haemato-biochemical alterations due to antioxidants and lipid peroxidase were consistent in the diagnosis and management of mammary tumors in bitches.EnglishVeterinary ScienceArticle