Singh, RajvirKumar, Ravindra2018-11-282018-11-281999http://krishikosh.egranth.ac.in/handle/1/5810084527The study was conducted on anatomical and histomorphological development of small intestine during prenatal life in 2lbuffalo fetuses.Gross anatomical study revealed that there is direct relationship between length and diameter of small intestine and crown rump length of foetus i.e. as the length of foetus increased, length as well as diameter of small intestine also increased.The histomophology indicated appearance of villi by 62 days in duodenum, 79 days in jejunum, 118 days in the ileum of buffalo foetus. The crypt of Liberkuhn (intestinal glands) were seen only in jejunum at 209 days.The epithelial lining was found to change from stratified cuboidal to simple columnar at 118 days in duodenum, 95 days in jejunum and 79 days in the ileum.The goblet cells were first seen at 95 days in duodenum, 118 days in the jejunum and 124 days in the ileum.The lamina muscularis mucosae developed at 198 days in jejunum and ileum and at 209 days in duodenurn.The duodenal glands were well differentiated by 159 days in the duodenum. The peyer's patches were first observed at 173 days and fully formed at 198 days in the ileum. The tunica muscularis was formed at 53 days in the duodenum and jejunum and 79 days in the ileum.The tunica serosa was found to develop at 53 days, 79 days and 118 days in duodenum, jejunum and ileum respectively.So pattern of development was cranio-caudal except lamina muscularis which followed caudo- cranial pattern of development.The goblet cells were showing strong AB\PAS reaction in developing stages.EnglishThesis