Kavitha Rani B.SUNIL KUMAR B. S.2023-12-162023-12-162021https://krishikosh.egranth.ac.in/handle/1/5810203605Studies on prevalence of cattle mortalities in Southern Transition and Hilly Zones of Karnataka with special reference to pathology of Mimosa invisa toxicity was conducted for a period of two years (2018-19 and 2019-20), at the Department of Veterinary Pathology, Veterinary College, Shivamogga. Incidence of non-infectious cattle mortalities were more than infectious causes, and bacterial, systemic / metabolic, plant poisoning causes of cattle mortalities were more in both STZ and HZ. Average age of death was 5-6 years and incidence in females were more in both STZ and HZ. In both zones, cattle mortalities due to infectious and systemic/metabolic causes were more during rainy season. Plant poisoning cases in STZ were more during winter and in rainy season in HZ. Pathomorphological studies on natural cases of Mimosa invisa in cattle revealed interstitial nephritis, focal glomerulonephritis, diffuse renal tubular necrosis, portal hypertension and sinusoidal congestion, hepatic vacuolar degeneration, cholangitis, multifocal interstitial pneumonia, bronchopneumonia, alveolar haemorrhages, pericardial and myocardial haemorrhages, focal pericarditis and myocarditis, and splenic hemosiderosis. Phytochemicals such as saponins, alkaloids, flavonoids, glycosides, tannins, phenolic compounds identified from Mimosa invisa were recovered from field condition. Serum biochemistry revealed elevated BUN, CRT, SGOT and proteinuria respectively. In the present study, the rate of morbidity, mortality and case fatality were 70 ± 12.28, 46.67 ± 3.34, 76.66 ±14.57 respectively. It may be inferred that Mimosa invisa induces toxaemic condition with haemorrhagic manifestation in cattle. Keywords: Southern Transition Zone, Hilly Zone, Karnataka, Mimosa invisa, Pathomorphology, Cattle mortality, Plant poisoningEnglishThesis