Sodhi, Simrinder SinghKaur, Amanpreet2021-11-252021-11-252021https://krishikosh.egranth.ac.in/handle/1/5810178291Pigs are an important part of livestock sector. The pig rearing economically supports the lower section of society. The pork is highly preferred due to its high nutritional value. The current study is based on the differential expression of genes (ACAT2, ACAA2, APOA4 & SOCS2) involved in metabolism and immune response in Large White Yorkshire (LWY) and indigenous pig where liver is taken as tissue of choice. The qualitative and quantitative analysis were done by gel-elctrophoresis and real-time qPCR. ACAT2 has shown significantly (P<0.05) higher mRNA expression in indigenous pig in comparison to LWY. Whereas, ACAA2 shows no significant difference (P<0.05) between both breeds with lower quantitative transcript levels in indigenous pig. APOA4 shows significantly (P<0.05) negligible mRNA expression with only 1% expression of LWY. SOCS2 shows significantly (P<0.05) lower mRNA expression in indigenous pigs than in LWY. Therefore, the current study on expression profile of genes under study can be one of the platforms to understand the differences of genetic mechanisms between indigenous breed and LWY.EnglishThesis