Vikrama Chakravarthi, PArivuchelvan, AJagadeeswaran, ATANUVAS2019-11-272019-11-272016http://krishikosh.egranth.ac.in/handle/1/5810136273TNV_IVJ_2016_93(5)17-19Present study was carriedout to explore the immunomodulatory activity of Allium sativum against Newcastle disease in native poultry birds. Five groups of  fty birds were divided equally and T1 and T2 group served as negative and positive control whereas T3, T4 and T5 groups were supplemented with 0.5, 1.5 and 3.0 % of A. sativum bulb powder in feed from 15th day to four months. Vaccination was carried out on 15th and on 90th day using commercial oral pellet vaccine. Blood samples were collected on 15th, 45th, 90th and 112th day and HI assay was carried out. The results have revealed that A.sativum groups produced signi cant HI titre than the control groups, hence it can be used as an immunomodulating agent in native poultry birdsenVeterinary ScienceArticle