dr. JAGADEESH S. SANGANALdr. JAGADEESH S. SANGANALKANIKA SUDHAKARENKANIKA SUDHAKAREN2022-09-012022-09-012019-08https://krishikosh.egranth.ac.in/handle/1/5810186929The present study was conducted to synthesis nanofibers from methanolic leaves extract of Simarouba glauca by an efficient protocol of electrospinning technique using a mixture of Polyvinyl pyrrolidine and S. glauca extract in various concentrations viz, 8%, 12% and 14%.The phytochemical analysis of the plant extract were done and showed the presence of various secondary metabolites such as carbohydrates, proteins, alkaloids, flavonoids, tannins, phenolics, glycosides, anthraquinones, phytosterols and triterpenoids. The physico-chemical properties and the interaction between the plant extract and the polymer were analysed using SEM and FTIR. The invitro antibacterial activity of the plant extract nanofibers were studied by using Kirby- Bauer disc diffusion assay. Results obtained from the study indicates that the synthesised plant extract nanofibers possess antibacterial property against food spoilage microorganisms. Also found that when the plant extract concentration in the nanofibers increased, the antibacterial property was increased. Hence, it was concluded that extract can be used as source of natural antimicrobial compouThe present study was conducted to synthesis nanofibers from methanolic leaves extract of Simarouba glauca by an efficient protocol of electrospinning technique using a mixture of Polyvinyl pyrrolidine and S. glauca extract in various concentrations viz, 8%, 12% and 14%.The phytochemical analysis of the plant extract were done and showed the presence of various secondary metabolites such as carbohydrates, proteins, alkaloids, flavonoids, tannins, phenolics, glycosides, anthraquinones, phytosterols and triterpenoids. The physico-chemical properties and the interaction between the plant extract and the polymer were analysed using SEM and FTIR. The invitro antibacterial activity of the plant extract nanofibers were studied by using Kirby- Bauer disc diffusion assay. Results obtained from the study indicates that the synthesised plant extract nanofibers possess antibacterial property against food spoilage microorganisms. Also found that when the plant extract concentration in the nanofibers increased, the antibacterial property was increased. Hence, it was concluded that extract can be used as source of natural antimicrobial compouEnglishThesis