Sankar, PalanisamyTelang, Avinash GopalRamya, KalaivananVijayakaran, KarunakaranKesavan, ManickamSarkar, Souvendra NathTANUVAS2018-06-052018-06-052014-07http://krishikosh.egranth.ac.in/handle/1/5810049268TNV_MBR_2014(1-10)enite (25 ppm) daily through drinking water for 42 days. Groups III, IV and V were maintained as in Group II, however, they were also administered empty nanoparticle, curcumin (100 mg/kg bw) and CUR-NP (100 mg/kg bw), respec- tively, by oral gavage during the last 14 days of arsenic exposure. On the 43rd day, genotoxic effects were evalu- ated in bone marrow cells. Arsenic increased chromosomal aberrations, micronuclei formation and DNA damage. Both free curcumin and CUR-NP attenuated these arsenic- mediated genotoxic effects. However, the result suggests that nanoformulation have better protective effect than free curcumin at the same dose level.enVeterinary ScienceProtective action of curcumin and nano-curcumin against arsenic- induced genotoxicity in rats in vivoMolecular Biology ReportArticle