Surendhar, MVijaya Bharathi, MSelvaraju, GRathnapraba, SRaj Kumar, RATANUVAS2019-10-312019-10-312019http://krishikosh.egranth.ac.in/handle/1/5810133626TNV_IJCS_2019_7(3)1349-1352Canine parvovirus enteritis is caused by canine parvovirus -2 (CPV-2), which is highly contagious and often fatal disease, characterized by vomiting, fowl smelling bloody diarrhoea and myocarditis in young dogs. In the present study, a total of 150 faecal and blood samples were collected from dogs with the symptoms of haemorrhagic gastroenteritis from Madras Veterinary College Teaching Hospital (MVCTH), Chennai to study the molecular epidemiology and haemato-biochemical changes in CPV-2 infected dogs respectively. Seventy one (47.33 per cent) dogs were positive for CPV-2 by PCR assay. Strain specific assay reveal CPV-2a and CPV-2c variants were recorded in 70 and 01 dogs respectively. Incidence of CPV-2c is the first report in Tamil Nadu. DNA sequencing was done for 8 PCR positive samples, out of which three were characterized as CPV-2c, indicating that this CPV type 2c is currently circulating in India.enVeterinary ScienceArticle