Gaikwad, R. V.Das Arjun2024-10-302024-10-302024-04-10https://krishikosh.egranth.ac.in/handle/1/5810215984The current study entitled “STUDY OF HEMORRHAGIC ENTERITIS IN CANINES” was carried out at the Department of Veterinary Epidemiology and Preventive Medicine, Mumbai Veterinary College, Parel, Mumbai-400012. The primary focus of the current research study was to evaluate different causal factors contributing to hemorrhagic enteritis, analyze hematobiochemical parameters, investigate their correlation, and assess the effectiveness of therapeutic interventions in canines. The study included 33 dogs showing symptoms of melena and/or hematochezia, as well as 10 apparently healthy dogs, without regard to breed, gender, or age. Further screening of all dogs for Canine Parvovirus or Canine Coronavirus using a Rapid CPV/CCV combo Ag test kit and for Canine Distemper using a Rapid CDV Ag test kit were done. Stool and blood samples were collected for routine and microscopic examination, as well as for estimating hematological and biochemical parameters. Among the clinical signs exhibited by the dogs, vomiting contributed 20% followed by melena 18%, diarrhea 16%, pain on abdominal palpation 15%, pyrexia 14%, hematochezia 11%, tenesmus 4% and Jaundice 2%. Treatment was administered based on the specific disease condition and underlying etiology using fluids, oral and parenteral antibiotics, anthelminthics and other supportive therapy. Canine Parvovirus was identified as the leading cause of melena and/or hematochezia in the examined dogs, followed by Ancylostoma caninum, Ehrlichia canis, uremic gastritis, Canine Distemper, Babesia canis, Trypanosoma, and Leptospirosis. The differences in hematological and biochemical parameters between diseased dogs and apparently healthy animals were statistically significant. Following the treatment, there was a notable improvement in hemato-biochemical parameters and clinical signs. One dog with abdominal mass and generalized lymph adenopathy died despite the treatment. The causes of hemorrhagic enteritis are diverse and multifactorial. Use of gut acting antibiotics like amoxicillin or ampicillin helped in the controlling of opportunistic bacteria in the gut.EnglishThesis