Subramanian, SaravananKondan Muthusamy, PalanivelGanapathy, SelvarajuPalani, SrinivasanTANUVAS2020-05-302020-05-302015-12http://krishikosh.egranth.ac.in/handle/1/5810146718TNV_JPAM_2015_9(4)3295-3298Humoral immune response elicited by administration of purified adjuvanted E. tenella sporozoites by S/C in neck region of broiler chickens in different age groups was assessed by a developed indirect ELISA. The chickens of group (T2) immunized with 25 μg of antigen with Freund’s Complete adjuvant (FCA) on day 2 and a booster vaccination without adjuvant on 18th day of age inducted peak IgG levels (0.616±0.022) at six weeks of age post immunization (PI) with a decline (0.394±0.012) at 7 weeks of age. A protective immune response against caecal coccidiosis could therefore be achieved by an immunization with adjuvanted E. tenella sporozoites in chickens of less than a week old, followed by a booster without adjuvant. Further, the performance of immunized chickens as indicated by mean weight gain (302.5±13.834g), mean lesion score (1.33±0.21) and mean oocyst output per gram (OPG) of faeces (53.84±19.09 x103) was found to be superior to the non- adjuvant vaccinated group and unimmunized infected control, however, the mean lesion score and OPG of faeces were inferior to that of medicated group.enArticle