Baba Prasath, NSelvaraj, JVishnugurubaran, DTANUVAS2021-08-312021-08-312018https://krishikosh.egranth.ac.in/handle/1/5810174884TNV_IJVP_2018_42(3)198-199A Holstein Friesian cow aged over four years was presented with a history of growth in the left eye. Physical examination revealed whitish grey, sessile, cauliflower like growth. The growth was removed and tissue pieces were processed for histopathology. Microscop— ically, the biopsy revealed finger like papillary projections covered by neoplastic stratified squamous cell with central thi.r\ fibrovascular stroma. Neoplastic cells were highly anaplastic with hyperchromatic nuclei and mitotic figures. The surface neoplastic cells invaded deeper into the stroma as cords and formed keratin pearls. Based on the histopathological features, the case was diagnosed as papilla- matous form of squamous cell Carcinoma.EnglishVeterinary ScienceArticle