Ponnusamy, P.Chitra, M. AnandaKumar, M. RanjithRamesh, A.TANUVAS2016-06-072016-06-072015-07http://krishikosh.egranth.ac.in/handle/1/66966A 2 year old female Jersey cross bred diary cattle was presented to the Teaching Veterinary Clinical Complex, Veterinary College and Research Institute, Orathanadu, Thanjavur Dt, Tamil Nadu with history of bilateral corneal ulceration, lymph node enlargement and bruxism. Samples were taken from affected eyes using a sterile swab for bacterial isolation and identification. Staphylococcus aureus was isolated and identified and it was found to be most sensitive to Tetracycline, Enrofloxacin, Gentamicin and Amikacin and resistant to penicillin, ampicillin and methicillin. Animal was treated with gentamicin systematically and locally and completely recovered with restoration of vision in 5 days of treatment duration.enCorneal ulcerMethicillin resistantStaphylococcus aureusAntibiogramArticle