Thangapandiyan, MPreetha, SPSuresh Kannan, SMohanapriya, TTANUVAS2021-10-042021-10-042016https://krishikosh.egranth.ac.in/handle/1/5810176601TNV_IJAS_2016_3(3)479-483An epizootic causing high morbidity and high mortality in Swiss albino inbred mice over a period of two weeks caused by Klebsiella pneumoniae is reported. Diagnosis was based on clinical signs, histopathological, bacteriological evaluation of the lung, kidney and intestinal tissue and multiplex PCR. Biochemical tests were positive for citrate, nitrate, urease, lysine decarboxylase, ornithine decarboxylase and negative for phenylalanine and hydrogen sulphide production. Carbohydrates viz., glucose, lactose, adonitol, arabinose were fermented but sorbitol was not. Disc diffusion tests for antibiotic sensitivity showed susceptibility to enrofloxacin, amikacin, doxycyline and resistant to cephalexin, cefadroxil, cefuroxime, cephtriaxone and ampicillin. Amplification by multiplex PCR for sulphydryl variable (SHV) gene yielded a product size of 472bp.EnglishVeterinary ScienceArticle