Meshram, M. D.Kamble Mahesh Siddharth2024-02-022024-02-022023-04-03https://krishikosh.egranth.ac.in/handle/1/5810206682Chlamydiosis is a contagious disease found in goats and it is zoonotic importance. It has no outward manifestation, it goes undiagnosed in most cases. The present study entitled “Therapeutic management of Chlamydiosis in goat” was carried out for the purpose of diagnosis and treatment of Chlamydiosis in goats. The study was comprised of 150 animals from the flocks having a history of abortion, stillbirths, and weak kids from the Shirwal, Dahiwadi and Baramati regions of western Maharashtra. Samples included were blood and serum from these animals. Seroprevalence was evaluated using i-ELISA. Out of 150 animals 18 were found seropositive by i-ELISA and comprehensive prevalence was found 12%. The highest prevalence was found in Dahiwadi i.e. 18%. Highest prevalence was found in females (does) i.e.12.48%. Prevalence in age group of 1-2 year was the highest i.e.15.38%. Anaemia was seen in 6 (33.33 %) goats and PCV was subnormal in 6 (33.33%). Total erythrocyte count (TEC) was elevated in 3 cases (16.66%). Leukocytopenia was found in 10 (55.55%) cases. Neutrophilia and lymphocytopenia was observed in 12 goats (66.66%). Animals found positive with i-ELISA were divided into 3 groups each having 6 animals. Group I was treated with Oxytetracycline @10mg/kg which is conventionally used antibiotic, Group II was treated with Tylosin @10mg/kg and Group III was treated with Meropenem @10mg/kg the latter two were alternative antibiotics used for the treatment. Out of these 3 antibiotics used, Meropenem showed the better results in mitigation of anti-chlamydial antibodies than Tylosin and Oxytetracycline comparatively. Hence, it can be suggested that Meropenem @10 mg/kg by IV routes can be used as alternative antibiotic to treat Chlamydiosis in goats.EnglishThesis