Sahai, B.N.Upadhyay, Aditya Narain2022-12-122022-12-121986https://krishikosh.egranth.ac.in/handle/1/5810190538Biochemical Immunological and therapeutic studies of gigantocotyliasis ExplanatumThe present study was undertaken to find out the effect of Gigantocotyle explanatum infection on biochemical, histochemical and pathological alterations in buffaloes, also immunological and chemotherapeutic studies were made. Simultaneously, incidence of G. explanatum in cattle and buffaloes; larval amphistomes in snails, Indoplanorbis exustus and Gyraulus convexiusculus and also certain aspects of biology of this conical fluke ware studied. BIOCHEMICAL STUDIES Serum of 18 buffaloes infected with G. explanatum alongwith 6 uninfected buffaloes were collected from local abattoir at Ranchi. Eighteen infected buffaloes were divided into three groups 6 in each lightly infected (1 50 flukes), moderately infected (51 200 flukes), heavily infected (>200 flukes) and uninfected buffaloes were maintained as controls. Total serum protein, albumin, globulin, albumin-globulin ratio, serum alkaline phosphatase, serum alanine aminotransferase, total serum bilirubin and conjugated bilirubins were estimated on blood serum alongwith glycogen levels in liver tissues of buffaloes. Total serum protein: A highly significant (p < 0.01) reduction of total serum protein in moderately and heavily infected (6.837 + 0.0131 6.316 + 0.008 g/100 ml) buffaloes was found as compared to those of uninfected controls (7.865+0.009EnglishThesis