P.V. TresamolJACKSON BENNY2020-09-172020-09-172018https://krishikosh.egranth.ac.in/handle/1/5810151412Bovine theileriosis is an economically important tick-borne protozoan disease that affects cattle all over the world. The present study titled “Clinico-therapeutic studies on bovine theileriosis” envisages diagnosis and treatment of oriental theileriosis in dairy cattle. Microscopical examination of stained blood smears from 187 animals revealed Theileria spp. piroplasms in 61 cases, inclusions suggestive of A. marginale in 18 cases, concurrent infection of theileria and anaplasma in 32 cases and piroplasms of Babesia bigemina in one animal. Blood smears from positive cases were later confirmed by Acridine orange staining. Genus specific PCR for Theileria spp. yielded positive results in 58 clinical cases and 37 in-contact animals. Out of 58 positive cases, 50 were confirmed as T. orientalis using species specific PCR. Among the in-contact animals, all 37 positive cases were positive for T. orientalis. None of the samples from 58 clinical cases and 37 in-contact animals yielded positive results of T. annulata. Major clinical signs observed were anaemia, pyrexia, lymph node enlargement, lethargy and drop in milk production. Haemato-biochemical analysis revealed anaemia with low Hb, PCV and TEC and hyperproteinaemia with hyperglobulinaemia in the affected animals. Treatment with single dose of buparvaquone @ 2.5 mg/kg BW intramuscularly was found to be more effective than two doses of long acting oxytetracycline @ 20 mg/kg BW intramuscularly 48 hours apart.EnglishThesis