Prabhavathy, H.TamilselvanJoseph, CeciliaTANUVAS2018-06-282018-06-282018-06http://krishikosh.egranth.ac.in/handle/1/5810055398TNV_IJSET_2018_7(3)835-838A 7-year-old, 32 kg, male golden retriever presented in Madras veterinary College, Teaching veterinary clinical complex, vepery with a history of regurgitation and ptyalism and it developed a progressively reduced exercise tolerance. Results from a complete blood cell count, serum biochemical profile, and urinalysis did not indicate any metabolic abnormalities. Thoracic radiographs revealed a normal distal cervical and thoracic megaesophagus, Haematological examination, blood glucose, serum calcium, sodium, and potassium were all within normal limits. An electrocardiograph was normal. Treated with Tablet. Pyridostigmine - 64 mg orally every 8 to 12 hours for two weeks with Antacids. Pan 40 mg before food for two weeks to minimize stomach acid damage to the esophagus when food is regurgitated from the stomach and advised with elevated feeding and Cisapride is given up to three times daily. The Bailey Chair was used by owner. This case report suggests that patients with megaesophagus due to myasthenia gravis and animal recovered with that oral medication along with adviced feeding and managemental practice.enVeterinary ScienceArticle