Balakrishnan, V SManoj JohnsonKAU2019-05-182019-05-181999171583http://krishikosh.egranth.ac.in/handle/1/5810103748PGA study of the metabolic profile in ketotic cows in field conditions was undertaken. Twenty field cases of clinical ketosis in crossbred cows which attended the outpatient unit of university veterinary Hospital, Mannuthy selected at random, were utilized for the study. Similarly twelve healthy dairy cows of identical field conditions during the vulnerable period of ketosis., i.e., within two months of calving, selected at random 90nstituted the control group. Samples of b19od, urine and milk from both healthy and ketotic animals were collected and analysed for various parameters using standard methods. economic loss was also carried out. Analysis of Data collected from the diseased animals indicated a high incidence among Jersey crossbreds during summer. Cows aged three to six years and in their second or third lactation showed more incidence. Most of the ketotic cows were within the first five weeks of calving~ , Other than the usual signs ~eported by earlier workers, frequent falling down and biting of chain, rope and crossbars of the manger were also noticed. The clinical data were in physiological limits. Examination of haemoglobin (Hb) and packed cell volume (PCV) did not reveal any significant difference between ketotic and healthy cows. Biochemically blood glucose, phosphorus, magnesium and total protein, albumin and globulin showed significant decrease and blood urea nitrogen and ketone bodies in blood showed significant increase among diseased cows. However serum calcium, sodium and potassium did not vary significantly among the two groups. Urine and milk from the both the groups were examined and varying concentrations of ketone bodies were detected. Various managemental aspects for the prevention and control of ketosis were discussed.ennullThesis