Jain, K.L.Dushyant Kumar2016-11-192016-11-192007http://krishikosh.egranth.ac.in/handle/1/86512The extensive use of deltamethrin a synthetic pyrethorids has led to increase in its residue in water. The primary aim of this study was to workout biomarkers which are measurable biological parameters that can change in response to toxicity exposure and amelioration of toxicity effects with in Cyprinus carpio. Sublethal dose level of deltamethrin studied in L. cerfies for behavioural and certain hematogoical changes with and without dietary supplement of Vitamin C ascorbic acid. Among behavioural changes the most distinct features was increasing exitation with increase positive in concentration as evident from the increase in operculum movements/minutes from 63 in controls to 83 at 0.006ppm of Depetamethrin. Among haematolgoical parameters the estimates of haemoglobin haemato crit, total orthrocytes counts and total levocyte count manifested significant reduction with increasing concentration of deltamethrin upto 23.70, 23.33, 23.07 and 30.48% respectively, likewise there have been marked decline in tissue proteins and lipids in muscles upto 37.93 and 13.33% respectively. The total muscle cholesterol however enhanced by 82.88% at 0.006 ppm of deltamethrin. There were also significant changes in the activity of glycolytic enzymes GDH & PDH showing respectively a decline up to 57.31 and 45.87% with the increase in concentration of the pesticide. The Ascorbic acid feeding of Ascorbic acid along with pesticide showed lesser toxicity effects showing relatively about 8 to 10% lesser changes in haematolgoical, Biochemical and enzymolgoical parameters. Maximum amelioration of toxicity effects was evident in haemoglobin and PCV contents among haematolgoical parameters and muscle cholesterols. Later showed an improvement by 26% with ascorbic acid voer the normal diet fed fish i.e. the cholesterol contents increased by 76.02% at 0.06 ppm with normal diet and 50.70% with ascorbic acid mixed diet. In a pesticide concentration. This studies thus clearly evidence the application of this haematoglocial and biochemical parameters in assessing toxicity effects and their amelioration with ascorbic acid.enPesticides, Acidity, Vitamins, Enzymes, Toxicity, Proteins, biological phenomena, Concentrates, Lipids, EnvironmentThesis