Dr. R. A. MathakiyaGolaviya Akash V.2021-07-282021-07-282019https://krishikosh.egranth.ac.in/handle/1/5810170998Among the infectious diseases of calves, acute gastroenteritis and neonatal calf diarrhoea are two major causes of mortality in neonates of farm animals caused by multiple etiological agents all over the world. Rotaviruses constitute the single major entity of potentially pathogenic gastroenteritis in animals and humans. Rotavirus is classified as a member of family Reoviridae, genus Rotavirus, with a distinct “cartwheel” structure when viewed in negative electron microscopy. Due to segmented nature of the Rotavirus RNA genome and wide host range, vast genetic and antigenic diversity exists amongst different isolates of Rotavirus. Bovine Rotavirus cause significant economic loss in the dairy and meat industry due to increased morbidity and mortality, treatment costs, and reduced growth rates. In neonatal calves, about 5-20% mortality rate is observed due to Bovine Rotavirus in calves. In India, the prevalence of Rotavirus in calf diarrhoea, below one month of age, ranges between 10-52%.EnglishThesis