JAGADEESH S SANGANALARUNKUMAR KORI2023-10-302023-10-302021-03https://krishikosh.egranth.ac.in/handle/1/5810199878The study was conducted to induce lactation with the help of hormones or drugs in unproductive dairy cattle. Two groups of cattle (Groups I and II, n=10) were treated with 0.1 mg/kg estradiol – 17 β and 0.25 mg/kg progesterone S/C for seven consecutive days. Group I animals were administered with dexamethasone (20 mg/day) and reserpine (5 mg TD/day) and Group II animals were administered with dexamethasone (20 mg/day) and metoclopramide (0.1mg/kg) IM, on days 14 to 17. Both the groups of animals were synchronized by double PGF2α protocol in 10 days apart prior to initiation of hormone therapy. Results revealed that the 90 day mean milk production in Group I and Group II were 326.44 ± 21.30 litres and 387.82 ± 19.40 litres, respectively. It was suggested that administration of progesterone and estradiol – 17 β with PGF2α, dexamethasone, reserpine or metoclopramide was a viable method of inducing lactation in unproductive dairy cattle. Synchronizing estrous cycles of cows prior to initiation of lactation-induction protocol with two injections of PGF2α 10 days apart, improved success rates of induced lactations. Cost-benefit analysis was more for metoclopramide than reserpine treatment group. Lactation in induced cows could be maintained with good nutrition and managemental practices.EnglishThesis