RAVINDRA, N. A. PATIL) B. G.)JAFARSAB2023-02-072023-02-072021-03https://krishikosh.egranth.ac.in/handle/1/5810193375A total of 34 cattle were evaluated for cardiac disorders of which 12, 14 and 08 were affected with pericarditis, lumpy skin disease (LSD) and foot and mouth disease (FMD) respectively. On clinical examination, pericarditis, LSD and FMD can be differentiated and assessed for cardiac involvement. The age-wise and sex-wise prevalence revealed that adult and female cattle were more prone to cardiac disorders except in LSD where males are more prone. Haematologically erythrocytopenia and anaemia in all the affected cattle whereas, leucocytosis with neutrophilia and lymphopenia was seen in pericarditis and profound leucocytopenia was observed in LSD affected cattle. Biochemical alteration such as increased levels of ALT, AST, ALP (except in FMD) and hypalbuminaemia in the affected cattle might be due to impaired hepatic function along with muscular and cardiac damage. Electrocardiographic changes recorded in these cattle were showing Low amplitude QRS complexes, ST segment coving, ST segment elevation, supraventricular tachycardia, sinus tachycardia, sinus bradycardia, VPC’s and seconddegree AV block. Further the extent of cardiac damage was assessed by bovine cTn-I assay indicated by significant increase in cTnI value (except in FMD) when compared to healthy cattle. Radiography revealed foreign body passing beyond diaphragm in pericarditis affected cattle and could differentiate traumatic and non-traumatic type. Echocardiography and ultrasound guided pericardiocentesis suggested type of pericardial effusions (serous, blood mixed, suppurative and fibrinous) and fibrin deposition in the pericardium. Necropsy findings and histopathological study confirms the cardiac disorders and revealed infiltration of inflammatory cells, haemorrhages and degenerative changes in the myocardium affecting cardiac function in bovines.EnglishThesis