Ramkumar PKSaravanan MKarthika Ket al.TANUVAS2023-11-022023-11-022023https://krishikosh.egranth.ac.in/handle/1/5810200195A two years old male Chippiparai Dog was presented to the Veterinary Clinical Complex, Veterinary College and Research Institute, Orathanadu with a history of progressive weakness in their appendicular muscles, along with an acute onset of retching and regurgitation. On clinical observation, animal was emaciated with uncoordinated gait but the reflexes were found to be normal and exhibited progressive weakness upon exercise. On neurological examination, absence of withdrawal and deep pain reflex along with ptosis of both the eyelids, sluggish menace reflex and extra ocular palsies were noticed. Contrast radiography revealed megaesophagus. On biochemical analysis hyperproteinemia and hyperglobulinemia were observed. Based on these clinical observations and radiography, the case was confirmed as Ocular form of Myasthenia Gravis. The animal was treated with Inj. Neostigmine @ 0.04mg/kg SC at 6 hourly interval and Tab. Micronized Progesterone @0.2 mg/kg PO SID for 2 weeks. After 14 days of therapy the dog showed mild improvement in gait with improved appetite and no emesis were observed.EnglishArticle