HAEMOSTATIC, HAEMATOBIOCHEMICAL AND ANTIOXIDANT PROFILING AS PROGNOSTIC MARKERS IN CANINE BABESIOSIS
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Date
2018
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Abstract
Anaemia is an imperative clinical sign of many systemic, infectious and parasitic diseases. Evaluating the cause and type of anaemia will provide adequate information about patho-physiology of diseases. Anaemia is one of the mandatory clinical manifestations of tick borne diseases. Canine babesiosis is a tick borne hemoprotozoan parasitic disease caused by apicomplexan parasites of the genera Babesia, which is characterized by haemolytic anaemia, jaundice, lethargy,pyrexia and haemoglobinurea. Pathogenesis of anaemia in canine babesiosis has a potential role in determining the prognosis of the disease. As the affected animals mainly suffer from haemolytic anaemia, there will be alterations in their systemic iron level. Hepcidin, being a systemic regulator of iron level in the body system its concentration may be altered during this condition and it can further aggravate the disease progression. Based on this hypothesis, a study was conducted to assess the haematobiochemical status haemostatic alterations, oxidative stress,changes in the level of hepcidin and to identify the blood prognostic markers in the affected animals.
Description
TNV_TH_MVM 16054_2018
Keywords
Veterinary Science