“STUDIES ON PHARMACOKINETICS OF CEFEPIME IN SURTI GOATS
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Date
2005
Authors
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Journal ISSN
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Publisher
Anand Agricultural University, Anand
Abstract
Cefepime, a fourth-generation semi-synthetic broad spectrum cephalosporin
has bactericidal action against broad range of bacteria including those that are
resistant to conventional antibacterial drugs. The present study was designed to
investigate pharmacokinetics of cefepime in Surti goats following single dose
intravenous and intramuscular administration at the dose rate of 10 mg kg-1 of body
weight. Drug concentration in serum was determined using High Performance Liquid
Chromatography (HPLC). Following intravenous and intramuscular administration,
the serum concentration-time curves were characteristic of a two compartment open
model.
Description
Keywords
Veterinary Pharmacology, studies