Cardiopulmonary and haematobiochemical alterations during ketamine or propofol anaesthesia in acepromazine-xylazine premedicated horses
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Date
2011-06
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Abstract
Twelve clinical cases of horses were randomly divided into group
I and group II consisting of six each. Xylazine (0.50 mg/kg
b.wt) and acepromazine (0.03 mg/kg) were administered i.v.
as pre-anaesthetics in both groups. Ketamine 2.20 mg/kg b.wt
and 0.05 mg/kg/min was used i.v. for induction and
maintenance of anaesthesia in group I. Propofol 2.0 mg/kg
b.wt and 0.15 mg/kg/min was used i.v. for induction and
maintenance of anaesthesia in group II. Cardiopulmonary and
haematobiochemical parameters were recorded before sedation,
after sedation, after induction and maintenance of anaesthesia
and after recovery. The heart rate was significantly higher in
group I, and the mean central venous pressure was
significantly higher in group II. Hyperglycemia and
hypoproteinemia were more with ketamine than propofol.
Considering the cost and the volume required based on the
cardiopulmonary and haematobiochemical parameters, it could
be concluded that ketamine being cost effective could be used
as induction and maintenance agent in anaesthetic procedures
requiring short duration of anaesthesia, whereas propofol could
be used in anaesthetic procedures requiring longer duration in
field ambulatory equine practice.
Description
TNV_IJVS_2011_32(1)23-26
Keywords
Veterinary Science