Magnetoferritin: A Novel Magnetic Protein Cage Nanocarrier
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Date
2019-02
Journal Title
Journal ISSN
Volume Title
Publisher
Excellent Publishers
Abstract
Nanotechnology is the rapidly expanding field and nanoparticles are omnipresent.
Biological nanoparticles are assembled from molecules or atoms synthesized in a
biological system. They include magnetosomes, lipoproteins, viruses, exosomes and
ferritins.. A typical instance of a protein cage possessing this native biological function is
ferritin. This engineered ferritin, which has the same architecture as natural H-ferritin, is
termed magnetoferritin. The iron storage protein ferritin consists of a spherical polypeptide
shell (apoferritin) and accommodates various metal ions. During the last two decades, the
manipulation of protein cages for the encapsulation of single inorganic nanoparticles into
their core to design novel hybrid bioinspired nanoparticles Such hybrid nanoparticles
represent an opportunity for advanced nanotechnology applications in the nanodevices,
disease diagnosis and therapy, drug delivery, vaccine development and bioassay.
Description
TNV_IJCMAS_2019_8(2)182-186
Keywords
Veterinary Science