Comparative Studies on Preemptive Meloxicam, Ketoprofen, Tolfenamic Acid and Flunixin for Managing Postoperative Pain in Dogs
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Date
2019-05
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Veterinary Association, Chennai
Abstract
The aim of the study was to compare the
postoperative analgesic effect of meloxicam,
ketoprofen, tolfenamic acid and flunixin following
soft tissue surgery. The study was conducted
in 24 clinical cases of dogs and were randomly
divided into four groups viz., group I, II, III
and IV. Meloxicam, Ketoprofen, Tolfenamic
acid and Flunixin were administered at the
dose rates of 0.2, 2.0, 4.0 and 1.0 mg per kg
body weight intravenously, in group I, II, III
and IV animals, respectively. After 15 minutes,
Midazolam was administered at the dose rate of
0.3 mg per kg body weight intravenously, to all
the animals. General anaesthesia was induced
with Propofol at the dose rate of 6 mg/kg body
weight in all the animals intravenously, and
maintained with Isoflurane. Ovariohysterectomy
(OHE) was performed in all the animals as
per the standard technique. The postoperative
analgesic effect was studied by visual analogue
score at various time interval of postoperative
period. Meloxicam provided better postoperative
analgesia up to 12 h of surgery and not produced
significant adverse effect in all the animals. It
could be safely used as a preemptive analgesic
in midazolam-propofol-isoflurane anaesthesia
for ovariohysterectomy in dogs.
Description
TNV_IVJ_May2019_96(05)_24-26
Keywords
Veterinary Science, Veterinary Surgery and Radiology