Efficacy of Allium sativum Linn. against strongyles in naturally infected sheep
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Date
2011-12
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Helminth infection is a major cause for reduced productivity in livestock. Strongyles
are the most common and the most pathogenic of the helminth parasites of sheep and goat.
Indiscriminate use of chemical anthelmintics to control helminths has resulted in parasites
refractory to chemotherapy. Therefore, phytomedicine with anti-parasitic properties offer an
effective alternative. The present investigation was carried out to assess the efficacy of Allium
sativum bulb extract (AsBE) at various concentrations (10, 20 and 30 mg ml-1) against strongyle
infection in sheep. The eggs per gram (EPG) of faeces were found to be within the range
425-435 prior treatment in the different groups (Groups I, II and III), which significantly
reduced post-treatment (PT). The faecal egg count reduction percentage (FECR %) calculated
were 96.12 ± 1.70, 98.91 ± 1.52 and 98.72 ± 1.21 %, respectively, in Groups I, II and III
PT which received AsBE orally @ 10, 20 and 30 mg ml-1. The haematological and biochemical
profiles revealed anaemia and hypoproteinaemia in the infected groups. However, after treatment
with AsBE, the infected sheep showed restoration of their haematological and biochemical
profiles. It was concluded that AsBE could find application in anthelmintic therapy in veterinary
practice
Description
TNV_JVP_2011_25(2)124-128
Keywords
Veterinary Science