Comparative Ecaluation of Butorphanol Tartrate and Propofol as Constant Rate Infusion in Laparoscopic Ovarictomy in Canine
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Date
2015
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MAFSU, Nagpur
Abstract
The research project entitled “Comparative Evaluation of Butorphanol Tartrate and Propofol as Constant Rate Infusion in Laparoscopic Ovariectomy in Canine.” was undertaken with the objective to study the effect of constant rate infusion of butorphanol tartrate and propofol during laparoscopic ovariectomy in canine and to evaluate the different haemato-biochemical changes during the surgery and anaesthetic procedure in canine. Total twelve dogs were presented for surgical interventions. The cases were divided in to two groups i.e. CRI of butorphanol tartrate consisting of six dogs (Group I) and CRI of propofol consisting of six dogs (Group II). In both the groups, Diazepam (0.2 mg/kg, IV) was administered 10 minutes before the administration of Propofol (5 mg/kg, IV) to each dog of both the groups and maintenance of anaesthesia was done by 1.5% isoflurane. Further, CRI of anaesthesia was done by either Butorphanol tartrate or Propofol in group I and II, respectively.
In both the groups laparoscopic ovariectomy was performed. Dogs were placed in dorsal recumbency in Trendelenburg position and insufflation was achieved with carbon dioxide. Three ports technique were used, one for scope and two for forceps and cautery. During this the ovarian pedicle and uterine horn along with vessels was grasped with grasping forceps and cauterized with cautery forceps and scissors were used to cut the vessels and around ovary.
Surgical parameters, Anaesthetic (CRI) parameters, Physiological parameters, and Hematological parameters were studied in both the groups during Diazepam-Propofol-isoflurane anaesthesia and CRI of anaesthesia.
Time taken for ovariectomy (in minutes) was 65.67± 11.65 and 62.17±7.82 in Groups I and II, respectively. The mean duration of CRI of anaesthesia was 76.67± 7.85 and 65.5± 7.35 (min) in Groups I & II, respectively. There was no significant difference seen for all the hemato-biochemical parameters in between the groups. In both the groups, during CRI and surgical procedure, there was significant difference seen for serum creatinine.
CRI of anaesthesia produced very good quality of anaesthesia and excellent degree of muscle relaxation in both the groups. The quality of recovery was smooth and fast in both the groups.
Results suggested that, the combination of anaesthetics along with CRI of anaesthesia are feasible for performing laparoscopic ovariectomy in canine. Thus, CRI of anaesthesia could be used as an alternative to each other as its appears to be the safe and effective combination of induction and maintenance of general anaesthesia for laparoscopic ovariectomy in canine and could be used as a day care surgery, allowing faster recovery to reduce the cost of postoperative management.
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