Development of Antibodies in Broiler Chickens Immunized with Adjuvanted Eimeria tenella Sporozoites
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Date
2015-12
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Abstract
Humoral immune response elicited by administration of purified adjuvanted
E. tenella sporozoites by S/C in neck region of broiler chickens in different age groups
was assessed by a developed indirect ELISA. The chickens of group (T2) immunized with
25 μg of antigen with Freund’s Complete adjuvant (FCA) on day 2 and a booster vaccination
without adjuvant on 18th day of age inducted peak IgG levels (0.616±0.022) at six weeks
of age post immunization (PI) with a decline (0.394±0.012) at 7 weeks of age. A protective
immune response against caecal coccidiosis could therefore be achieved by an
immunization with adjuvanted E. tenella sporozoites in chickens of less than a week
old, followed by a booster without adjuvant. Further, the performance of immunized
chickens as indicated by mean weight gain (302.5±13.834g), mean lesion score (1.33±0.21)
and mean oocyst output per gram (OPG) of faeces (53.84±19.09 x103) was found to be
superior to the non- adjuvant vaccinated group and unimmunized infected control,
however, the mean lesion score and OPG of faeces were inferior to that of medicated
group.
Description
TNV_JPAM_2015_9(4)3295-3298