In vitro anti-oxidant and anti-microbial activity of aqueous extracts of Indian Brown Seaweed- Sargassum sps.
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Date
2020-02
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Abstract
The application of seaweed antioxidants in foods, food supplements, nutraceuticals and medicine
is considered from the perspective of benefits to human health. Similarly, the metabolites produced from
seaweed show antiviral, antiprotozoal, antifungal, and antibacterial properties aiding in the protection against
different environmental stresses. With this background, the study was conducted to explore the anti-oxidant
and anti-microbial activity of Indian brown seaweed- Sargassum sps viz. S.polycystum, S. tenerrimum and
S.cinctum collected from the ocean of Gulf of Mannar (Mandapam coast). The in-vitro antioxidant activity of
the seaweed extracts were assessed by DPPH scavenging activity and antimicrobial activity by Agar Gel Disc
Diffusion test against Gram (+) ve (Staphylococcus aureus and Bacillus cereus) and Gram (-) ve (E coli and
Pseudomonas aeroginosa) organisms at a stock concentration of 2000 μg/ml. Aqueous extracts of Sargassum
tenerrimum exhibited higher anti-oxidant potential as revealed by 50% DPPH radical inhibition, at a lower
working concentration of 800 μg/ml compared to other species which exhibited 50 % inhibition at 1200 μg/
ml. Similarly S.tenerrimum was observed to have higher anti-microbial activity which was evident from the
higher zone of inhibition at a concentration 200 μg/disc against Staphylococcus aureus (12.5mm), Bacillus
cereus (11 mm), E coli (14 mm) and Pseudomonas aeroginosa (12 mm). The results of this study revealed
the potential benefits of Sargassum tenerrimum as an anti-oxidant and anti-microbial which could be utilized
to develop functional meat products.
Description
TNV_20thMVC_PP_Feb-2020_OP15
Keywords
Veterinary Science