Comparative Evaluation of Bupivacaine, Zylazine and Xylocanine for Lumbo- sacral epidural Anesthesia in Pigs
Loading...
Date
2001
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Birsa Agricultural University, Ranchi
Abstract
1.Xylocaine @ 1 ml/5 kg body weight produced moderate analgesia and sedation permitting surgery of short duration.
2.Xylazine @ 3 mg/kg body weight produced moderate analgesia and satisfactory sedation permitting surgery of comparatively longer duration than that of Xylocaine.
3. Bupivacine @ 2 ml/5 kg body weight produced excellent analgesia, satisfactory sedation and deep muscle relaxation for a longer period, facilitating surgery of varying magnitude and longer duration upto posterior thoracic region.
4. Hyperglycemia was not a consistent feature following epidural administration of the anaesthetic agents. Variable levels of elevation in different groups was mild, transient in nature and normalcy could be restored in all the animals by 24 hours.
5.Serum creatinine, urea and AST level manifested alterations within. the physiological range even though at some stages of observation they were statistically significant.
6. Hypothermia was not a feature with Xylocaine and Bupivacaine. anaesthesia. Moderate rise in temperature with these agents was well compensated by 120 minutes. However, administration of Xylazine induced significant hypothermia.
7. Safe and satisfactory anaesthesia could be induced at the dose levels evaluated in this experiment to facilitate surgery of post thoracic regions employing Bupivacaine, Xylazine and Xylocaine in that order.